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Pancreatitis : An association between GLP-1-based therapies and acute pancreatitis has been observed, though a definitive causal relationship has not been established
Contact your healthcare provider if you experience: Signs of hypothyroidism : increased fatigue, cold intolerance, constipation, weight gain despite semaglutide, depression, or cognitive changes Signs of hyperthyroidism : anxiety, tremor, palpitations, heat intolerance, unexplained weight loss beyond expected, or insomnia Severe gastrointestinal symptoms : persistent nausea, vomiting, or diarrhea that might affect medication absorption Hypoglycemia symptoms : shakiness, sweating, confusion, or dizziness (particularly if also taking insulin or sulfonylureas) Maintain a consistent schedule for taking levothyroxineideally at the same time each day
Gao L, Huang H, Zhang L, et al
However, theoretical considerations and emerging evidence from related conditions suggest both potential benefits and important safety concerns that warrant careful evaluation
modelling, visual predictive checks over each trial and across trials, mean model predictions across trial arms and individual fits over time
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