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DALDA treatment significantly downregulated these genes in the ipsilateral spinal cord, comparable to ibuprofen, indicating suppression of inflammatory signaling pathways

Furthermore, glutamine-derived fumarate, malate, and citrate are significantly increased when glucose is deprived, demonstrating that glutamine drives the glucose-independent TCA cycle in a nutrient-poor tumor microenvironment (Le et al., 2012)

Consistent with this model, serum samples from G6PD-d patients have been reported to have significant increases in oxidation specific epitopes (OSE) [i.e

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