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Overall, at week 88, participants with 75% or more weight regain after tirzepatide withdrawal reversed cardiometabolic parameters to baseline (week 0) values, the team write, although they note those with up to 50% weight regain still showed improvements in these areas compared with the start of the study

Common side effects may include: Redness or irritation at the injection site Fatigue Nausea If you experience severe side effects or allergic reactions, seek medical attention immediately