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It is individualized, symptom-driven, and often used for inflammation, autoimmune conditions, or psychiatric symptoms rather than weight loss

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[PubMed] [Google Scholar] 81.Robert A., Lum J.T., Lancaster C., Olafsson A.S., Kolbasa K.P., Nezamis J.E

Need lower dosing or fewer side effects

Providers Clinicians will need to prepare for increased administrative burden related to navigating prior authorization demands

It acts as a selective inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme expressed in multiple tissues including adipose tissue and the liver that plays a role in cellular energy metabolism and fat storage