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Because many toxins (and drug metabolites) are eliminated via bile, smooth bile flow is critical, sluggish or inadequate bile production is very common in pets, and causes toxins to linger in the liver

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*Correspondence: Xiaodan Zhai, [email protected] These authors have contributed equally to this work and share first authorship Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers