But that glimpse did not disappoint
5, with the cost of the starting 1.5-mg dose set at $149 per monthor about $5 per dayfor cash-paying patients
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Specifically, the backs of the mice were first depilated with an animal depilatory cream to expose the extent of the trauma
Viability was assessed by Zombie UV Fixable Viability Dye (BioLegend) and cytokine production was measured by intracellular cytokine staining after 3 h stimulation with PMA (50 ng ml 1 ) (BioGems) and ionomycin (1 g ml 1 ) (BioGems) in the presence of brefeldin A (1 g ml 1 ) (GolgiPlug, BD Biosciences)
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