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And research has shown that cardiovascular disease and obesity-related type 2 diabetes are the usual suspects

10.1152/jappl.1999.87.3.982 72 KraemerW

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In 2013, alcohol-impaired driving fatalities accounted for 10,076 deaths (30.8 percent of overall driving fatalities) in the U.S

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Because gastrointestinal side effects including nausea, vomiting and constipation increase at higher levels, and the article says a lower amount with sustained adherence often outperforms a higher one that causes intolerable effects or is stopped early