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Importantly, discontinuation of semaglutide after 20 weeks of treatment led to regain of body weight, whereas maintaining treatment led to continued body-weight loss over an additional 48 weeks of treatment, underlining that life-long treatment is necessary to maintain treatment effect [37]

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[DOI] [PMC free article] [PubMed] [Google Scholar] 22.Wang J, Liu Y, Wang Y, Sun L