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Utilizing this methodology, several reports provide convincing evidence that endogenous GLP-1 released in the VTA and the NAc is in fact necessary for food intake control and blockade of its signal can lead to increased food intake (Dossat et al., In the previous paragraphs we have reviewed evidence for the clear suppression of food intake by mesolimbic GLP-1 activation

doi:10.1074/jbc.M116.721977

doi:10.3390/ph14100991 11

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