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GPx, the final antioxidant enzyme, catalyzes the reduction of H 2 O 2 or organic hydrogen peroxide to H 2 O or alcohol in the presence of reduced glutathione (188)

The combined quinone redox glutathione metabolism model can be used to simulate experimentally challenging scenarios such as potential redox cycling toxicity, while providing a platform from which quinone exposure and concentration toxicity experiments may be guided

Histopathological examinations at two months revealed well-defined cartilage formations earlier than usual (Fig