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[4] Treatment of individuals with glutathione synthetase deficiency generally involve therapeutic treatments to address mild to severe symptoms and conditions

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hence, maintenance therapy with enteral sodium hydrogen carbonate is administered orally after the patient has stabilized ( The survival prognosis of patients with GSSD largely depends on early diagnosis and treatment ( 4

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Results LNP-mRNA system We optimized the LNP component to improve transfection efficiency by replacing cholesterol with an equal amount of -sitosterol (Fig