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In a rat model of unilateral nephrectomy and doxorubicin-induced nephropathy, a HKC dose of 0.5 and 2 g/kg is administered via an intragastric (IG) manner for 28 days

Retatrutide remains in clinical development and is not approved for general prescribing or self-administration in the UK

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Specific defensive mechanisms may be triggered by tissue damage resulting from ROS production

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