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J Nucl Med (2007) 48(5):73643

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In healthy tissues, glutathione is mostly found in its reduced form

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The acronym PICO stands for population (individuals with BED), intervention (administration of GLP-1 agonists in individuals with BED), comparison (individuals with BED who received a placebo, lifestyle interventions, and other medications excluding GLP-1 agonists), and outcomes (effectiveness of GLP-1 agonists, particularly about weight loss) as reported in the articles