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Lehrke M, Broedl UC, Biller-Friedmann IM, et al

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2001;85(1):F702

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Rather than acting only as a scavenger of free radicals, glutathione participates in maintaining the redox environment necessary for normal mitochondrial signaling and enzyme activity

Increased oxidation of acetaminophen after starvation is also due to induction of CYP450 isoforms that start to convert more APAP to the toxic metabolite NAPQI [43]