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The inclusion of known control agonists within the screening set served to verify that the docking setup was able to recover ligands with established GLP-1R activity, thereby supporting the reliability of the prioritization strategy

Efficacy and safety of setmelanotide, an mc4r agonist, in individuals with severe obesity due to lepr or pomc deficiency: single-arm, open-label, multicentre, phase 3 trials

L-methylfolate: Targeted therapy begins

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