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Abbreviation PI Paralytic ileus T2D Type 2 diabetes GLP-1RAs Glucagon-like peptide-1 receptor agonists MR Mendelian randomization GWAS Genome-wide association studies SGLT-2 Sodium-glucose cotransporter-2 HbA1c hemoglobin A1C GTEx Genotype-Tissue Expression IVW Inverse-variance weighted GRCh37 Genome Reference Consortium Human Build 37 Chr Chromosome EA Effect Allele NEA Non-Effect Allele NES Normalized Effect Size SE Standard Error OR Odds ratio LD Linkage Disequilibrium Footnotes Declarations The authors declare that they have no conflict of interest

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