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There is some debate about whether to use ApoB or non-HDL cholesterol (which is the total cholesterol minus the HDL cholesterol)

BMC Nutr 2024;10:3

Many of the peptides making headlines today are synthetic, meaning they're made in a lab to mimic or enhance signals that already exist in the body

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The practical takeaway: AOD-9604 has a clean safety profile in trials but a failed Phase 2b efficacy endpoint

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