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Dual incretin agonists achieve greater weight reduction than GLP-1RAs alone, and tirzepatide has now demonstrated cardiovascular safety noninferior to a proven GLP-1RA in patients with ASCVD as well as benefit in obesity-related HFpEF [40, 45]

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I was surprised at how quickly they felt better (despite being sick for a very long time), and were able to reintroduce more food, fun, and joy into their lives

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