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Some studies suggest tirzepatide has slightly higher rates of nausea, though differences are small
Clinical trials show tirzepatide produces average weight loss of 20.9% over 72 weeks at the highest dose, compared to 3.3% with placebo
While GLP-1RA has proven clinical efficacy, the need for more comprehensive studies, to ensure their long-term safety, is essential to optimize their therapeutic role and improve patient outcomes on a global scale
The present commentary is intended not as policy guidance but as an interdisciplinary reflection
DOI:10.3389/fphar.2021.627533
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