The researchers speculated that the increased lean body mass was due to more efficient muscle protein synthesis from the less-degraded l-citrulline in the bloodstream
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Autophagy, which facilitates substrate breakdown, is created when autophagosomes attach to lysosomes
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10.3389/fendo.2018.00802 Summary Keywords hepatocytes, hepatocyte-like cells, induced pluripotent stem cells, growth factors, small molecules Citation Asumda FZ, Alzoubi S, Padarath K, Jones K, Kolhe R, Mondal AK, Alptekin A, Zhi W, Lee TJ, Huebert RC, Staff NP, Roberts LR and Kirkeby LA (2025) Comparative analysis of small molecule and growth factor-derived human induced pluripotent stem cell-derived hepatocyte-like cells