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The literature search was done by HBG, MS, AJ, HB, and ABMK

Cells were then gently washed with Dulbeccos phosphate-buffered saline (DPBS) to remove serum-containing media and treated with peptide 2012, peptide 2020, or defactinib in triplicate replicates

MOTS-c and Longevity Research Mitochondria are central to the aging process because they regulate energy production, oxidative stress, and cellular survival

These doses are well tolerated and have no meaningful toxicity risk, as excess B12 is excreted in urine rather than accumulating in tissues

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