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Definitions and diagnostic criteria for clinical obesity A recent expert group reviewed the utility of BMI-based measures for assessing individual health and concluded that these can misclassify (both underestimate and overestimate) adiposityand thus undermine effective clinical care and policy development [263]

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When administered under professional supervision, this treatment is generally well tolerated and considered safe for most individuals

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Key Research Applications and Observed Effects Clinical and preclinical investigations highlight retatrutides profound impact on body composition and metabolic health

A recent study showed a 14% reduced risk of substance use disorders when taking GLP-1s in those without a history of substance use disorders