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In pooled data from nine clinical trials, canagliflozin was associated with bone fractures (1.4, 1.5, and 1.1/100 patient-years for canagliflozin 100, 300 mg, and comparators, respectively) [45]

It is, therefore, important to provide primary care clinicians with the clinical evidence as well as a simple and pragmatic tool that could aid the decision-making process

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Chris Owens says he knew what healthy eating looked like in theory, but it felt like food noise had hijacked his brain

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