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These results were consistent with the findings of elevated urinary levels of the marker of lipid peroxidation, isoprostane F 2 -VI, the marker of platelet activation, 2,3-dinor-thromboxane B 2 , and the marker of endothelial activation, 6-keto-prostaglandin F 1 in 26 children diagnosed with ASD [117]

Collectively, these findings position glutathione at the convergence of oxidative stress regulation, mitochondrial function, vascular integrity, and cardiometabolic balance