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The current trial had a higher proportion of males at 35%, especially compared to the STEP non-diabetes trials, which included 19-26% males

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The gut-brain axis is the connection between the brain and the digestive system

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A still unsolved issue, connected with the role of carnitine in modulating gene expression (Figure 1) is the link between mitochondria and nucleus: acetylcarnitine produced in mitochondria would reach the nucleus providing acetyl units (Figure 2)

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