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doi: 10.1016/j.ultsonch.2023.106677 53 AhangariHKingJWEhsaniAYousefiM

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GLP-1 receptor agonists like semaglutide work by slowing stomach emptying and signaling fullness to your brain, but this same mechanism can trigger loose stools or diarrhea in roughly one in four patients during the first weeks of treatment

While semaglutide and tirzepatide are helpful for people who struggle with type 2 diabetes, people suffering from obesity or who have at least one weight-related condition can also benefit immensely from these medications

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Semaglutide improves insulin sensitivity primarily through GLP-1 receptor-mediated reductions in glucagon secretion, improved beta-cell function, and indirect effects from weight loss