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The mitigation of apoptosis and dampening of inflammatory responses further contribute to this protective aspect

(ref) Chang CH, Tsai WC, Lin MS, Hsu YH, Pang JH

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According to Mankin et al, the rigorousness of the OA destruction was categorized using the histologic standards (Table 2) based on structural variations (scale range 06), cellular variations (scale range 03), damage of safranin O staining (scale range 04) and tidemark integrity (scale range 01) by 3 independent researchers

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