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By inhibiting the cystine transporter (xCT), erastin inhibits the uptake of cystine

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The schistosomicidal activities of PZQ and of potassium antimonial tartrate, a drug used in the past for schistosomiasis and a TGR inhibitor, are reduced in immunosuppressed mice 65 , indicating a crucial role of the host immune system in the mechanism of action of schistosomicidal agents in vivo

10.1515/mr-2023-0028 [DOI] [PMC free article] [PubMed] [Google Scholar] Wei L., Lin Q., Lu Y., Li G., Huang L., Fu Z., et al