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It blocks DNA methylation by inhibiting DNA methyltransferase and induces cell cycle arrest in the G2/M phase through the p53-independent pathway in human cancer cells

no KLOW trial Community approach Long extension Reported duration Up to 16 weeks Reported break 4+ weeks Evidence level Anecdotal

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coli coincidentally lacking both TrxR and Gsr (TrxR/Gsr-null) cannot support replication, although spontaneous TrxR/Gsr-null suppressor mutants are readily isolated (Fig

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