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Mn overexposure also reduces glutamate receptor expression, NMDAR, in neurons in vitro and in vivo , potentially exacerbating glutamate-induced excitotoxicity (Wang et al., 2017

[DOI] [PubMed] [Google Scholar] 108.Mamalaki E., Ntanasi E., Hatzimanolis A., Basta M., Kosmidis M.H., Dardiotis E., Hadjigeorgiou G.M., Sakka P., Scarmeas N., Yannakoulia M

SVM performance was lower for urinary and gait domains compared to the cognitive ( Figure S5A, C ), with urinary models reaching mean ROC AUC = 0.733 0.008 and PRC AP = 0.866 0.008, and gait models achieving mean ROC AUC = 0.722 0.003 and PRC AP = 0.823 0.003

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Research discussions around BPC-157 often include cytokine activity, oxidative stress markers, inflammatory mediator balance and tissue protection models