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According to the Summary of Product Characteristics and clinical trial data, these include: Nausea often most pronounced during dose escalation Diarrhoea can range from mild to moderate severity Vomiting particularly in the initial weeks of treatment Constipation affecting a significant proportion of users Abdominal pain or discomfort Decreased appetite which contributes to weight loss Dyspepsia (indigestion) These gastrointestinal symptoms typically diminish over time as the body adjusts to the medication

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When taking both medications, monitor your blood sugar levels closely, especially if you have diabetes

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