Growth hormone, for its part, increases cellular replication, encourages collagen synthesis in your skeletal muscles, and stimulates the production of a separate hormone called insulin-like growth factor-1 (IGF-1), which helps regulate the process by which your body creates fat.1 2 3 Given these qualities, a higher concentration of circulating growth hormone can lead to improved exercise training, increased muscle strength, and a decreased propensity for fat accumulation.4 Despite belonging to the same category and effecting a common outcome, CJC-1295 and ipamorelin have distinct mechanisms of action: CJC-1295s mechanism of action CJC-1295 mimics a chemical from the hypothalamus called growth hormone-releasing hormone (GHRH), which tells the pituitary gland to release growth hormone.5 Ipamorelins mechanism of action Ipamorelin is an analog of ghrelin, a hormone originating from the cells in your stomach.6 As such, it binds to the brains ghrelin receptor and, like GHRH, stimulates growth hormone secretion from the pituitary
Adv Sci, 2020, 7: 2001335 Ai L, Pei Y, Song Z, et al
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10.3310/hta15suppl1/09 [DOI] [PubMed] [Google Scholar] Soto J., Gmez A., Vsquez M., Barreto A., Molina K., Zuniga-Gonzalez C
Lamhonwah A-M, Tein I (2020) Expression of the organic cation/carnitine transporter family (Octn1,-2 and-3) in mdx muscle and heart: implications for early carnitine therapy in Duchenne muscular dystrophy to improve cellular carnitine homeostasis
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