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[275] Alcohol may initially cause drowsiness but can disrupt sleep quality and interfere with melatonins ability to maintain sleep throughout the night

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[8] This does not establish causation from exogenous secretagogue use, but it informs the monitoring rationale for keeping IGF-1 within the upper physiologic range (150 to 300 ng/mL in adults) rather than pushing it supraphysiologic

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