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High levels of estrogen can sometimes interfere with the hormone prolactin, which is responsible for making milk

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The primary outcomes were revised 5-point MACE consisting of myocardial infarction, stroke, hospitalization for heart failure, coronary revascularization and all-cause mortality

This stage benefits from: A clear protein target mindset Portion awareness without restriction language Consistent hydration between meals Simple grocery structure Backup snacks for busy days Think of this phase as habit reinforcement, not food tightening

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The statistical testing strategy for the confirmatory secondary end points used a separate alpha spending function to control type I error rate at a 1-sided level of 2.5%, which aligned with the P value adjustment for the group sequential design