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(Reference Theofilis, Vordoni and Kalaitzidis13) comprehensively evaluated the levels of TMAO in NAFLD, revealing that NAFLD patients exhibit notably elevated circulating TMAO concentrations compared with those without NAFLD

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However, the extent of its long-term safety in humans remains a subject of ongoing investigation

Chang J, Leong RW, Wasinger VC, et al

There are no documented interactions between the peptides discussed in this guide and biologic therapies like dupilumab

Specifically, CLP-induced systemic inflammation may activate microglia to secrete pro-inflammatory mediators, which suppress the Nrf2/HO-1/GPX4 redox axis, triggering mitochondrial dysfunction and oxidative stress