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As Mounjaro will be prescribed for weight loss on the NHS over the next 12 years, these medications are set to become even more popular

At the federal level, Senator Banks of Indiana introduced S.3794, the SAFE Drugs Act, which would create tighter controls over compounding activity across the county

OGTT, oral glucose tolerance test

GLP-1 helps to regulate blood sugar by encouraging more insulin to be released from the pancreas, says Monica Amin, PharmD, a pharmacist at Marley Drug and Medicure in Winston-Salem, North Carolina

This approach could potentially mitigate the loss of lean mass commonly seen with incretin therapies, a critical consideration for long-term metabolic health and physical function

To address them, the field is rapidly developing new frameworks, as seen in recent perspective papers we published, discussing "clock-to-clock" analysis and using diseases as a testbed for longevity interventions