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This distinction is critical when considering the question, what dose of semaglutide is equivalent to tirzepatide. Potency and Efficacy: Tirzepatides dual receptor activity generally results in higher potency and, as clinical trials suggest, often leads to greater reductions in HbA1c and body weight compared to semaglutide

If your stomach normally empties in two hours and semaglutide slows it by 30%, your new emptying time is about 2.6 hours

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Nutrition Journal, 22 , 68