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A number of studies in the 1990s confirmed dysregulation of PKC isoforms in symptomatic bipolar disorder, with the most consistent finding being an increase in PKC activity associated with manic symptoms

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Uric acid can interact with reactive oxygen species (ROS), such as hydroxyl radicals and hypochlorous acid, transforming them into less harmful substances such as allantoin, allantoate, glyoxylate, urea and oxalate (8)

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Human pancreatic neuro-insular network in health and fatty infiltration