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In addition to these established topical options, emerging evidence suggests that topical amitriptyline may provide clinically meaningful pain relief with acceptable tolerability in BMS, whereas topical doxepin has demonstrated analgesic efficacy in head-and-neck mucositis pain in randomized trials 19,20

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In Outlive, Attia states that he wants his clients to aim for a VO2 max score in the Elite zone for their gender but two decades younger