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Distinct subpopulations of head and neck cancer cells with different levels of intracellular reactive oxygen species exhibit diverse stemness, proliferation, and chemosensitivity

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This process, which could be stimulated under conditions of stress, envisages a chloroplastic sequence of reactions involving H 2 O 2 -triggered S -glutathionylation of diverse available protein cysteine residues, followed by regeneration of the free cysteines by glutathione-dependent GRX (Zaffagnini et al., 2012)

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