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The operators who figure this out first are going to absolutely clean up

Neurobiol Aging (2018) 64:3343

Although numerous studies have compared the available GLP-1 receptor agonists, few have directly explored the effects of switching between these agents, highlighting a need for further research

The solution isnt to avoid prescribing them

We followed up on two hits that exhibited the strongest GxE interactions, SLC25A19 and SLC25A32, which are transporters of two B family vitamin-derived cofactors, thiamine pyrophosphate (ThPP, or vitamin B 1 ) and folate species (vitamin B 9 ), respectively

It should also be acknowledged that preventive strategies that make people healthier means they will live longer, and even as more is understood regarding healthy aging and cognitive decline, age remains one of the strongest risk factors for AD/ADRD