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Notably, NAC has been shown to activate Sxc [111, 112] and to induce the expression of GLT1 [113]

Berberine alleviates liver fibrosis through inducing ferrous redox to activate ROS-mediated hepatic stellate cells ferroptosis

doi: 10.1002/hep4.1309

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Once outside the cell, GSH degradation occurs exclusively in the extracellular space and only on the surface of cells that express the ectoenzyme -glutamyl transferase