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The guidance outlines five key recommendations relating to GLP-1RAs and GLP-1/GIPRAs and sedation or anaesthesia: All patients should be asked about the use of GLP-1RAs and GLP-1/GIPRAs before anaesthesia or sedation for surgical and endoscopic procedures and be involved in discussion and planning regarding the risk of aspiration

There is no need to inform your pharmacy or get a new prescription

The litigations further allege that manufacturers failed to adequately warn patients and prescribing physicians about potential risks associated with these drugs despite emerging safety reports, adverse event data, and growing medical concern surrounding gastrointestinal and optic nerve injuries

More serious but rare side effects include: Pancreatitis (inflammation of the pancreas) Gallbladder problems Changes in heart rate While these serious complications are uncommon, they underscore why these drugs require medical supervision

Theres no reason to stop a medication that is otherwise working well. Oral side effects on semaglutide, tirzepatide, and other GLP-1s occur often enough to be worth talking about