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In a house dust mite-induced NC/Nga mouse model (a spontaneous AD model), quercetin has been reported to activate the PPAR signaling pathway, which may contribute to the improvements in lipid biosynthesis, inflammatory status, and barrier integrity (Karuppagounder et al., 2016)

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They constructed an immune-related regulator y axis involving XIST and OIP5-AS1/miR-216a/PIK3CA, which may play a critical role in regulating ferroptosis during AMI progression