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Plant Physiol 109:10471057 Gollan PJ, Trotta A, Bajwa AA, Mancini I, Aro E-M (2021) Characterization of the free and membrane-associated fractions of the thylakoid lumen proteome in Arabidopsis thaliana

Starting on a low dose and increasing slowly gives your body time to adjust, making the side effects more manageable and treatment more tolerable overall

An earlier landmark study by Staresinic et al

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Do not rub the site afterward