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Hypertension 53 , 668673 (2009)

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Peptide Therapeutics: Current Status and Future Directions. Drug Discovery Today , 20(1), 122-128, 2015

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Knockdown of LONP1 in alveolar type 2 (AT2) cells induces the expression of senescence-associated secretory phenotype factors [i.e., plasminogen activator inhibitor-1 (PAI-1) and transforming growth factor- (TGF-)], as well as senescence markers (such as p53 and p21), and leads to G2 phase cell cycle arrest [71]