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The key principle is to reduce slowly and monitor continuously, treating any upward weight trend as a signal to pause the reduction or increase one step

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Trends Endocrinol Metabol: TEM (2016) 27(6):42738

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Mounting evidence suggests that GLP-1 RAs have benefits beyond reducing blood glucose that include improving kidney function in people living with type 2 diabetes mellitus (T2DM) and chronic kidney disease (CKD), a common microvascular complication of T2DM

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Seales adversas reportadas en literatura Nausea(moderado) Reportada en SURMOUNT-1: 29% brazo 15mg vs 16% placebo

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Glucagon receptor activation increases metabolic rate by stimulating thermogenesis in brown adipose tissue and enhancing mitochondrial activity in hepatocytes and skeletal muscle

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The first injection was nerve-wracking, but way easier than I expected

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