melatonin with glutathione Essential Therapeutic Comparative effects of melatonin, glutathione

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Reactive oxygen species can attack biomembranes, enzymes, proteins, and nucleic acids (Venditti et al., 2013)

DJ-1, a cancer- and Parkinson's disease-associated protein, stabilizes the antioxidant transcriptional master regulator Nrf2

Furthermore, Gclc -deficient FoB have a block in the mitochondrial electron transport chain (ETC) due to diminished complex I and II activity and thereby accumulate the tricarboxylic acid cycle metabolite succinate

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Targeting glutamine metabolism transporter inhibitors Gln metabolism has received increasing attention in the process of material transport and energy metabolism in cancer cells, and increased Gln catabolism in cancer cells has been associated with increased expression of Gln transporter proteins