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Dietary adjustments are often the first line of self-management: Eat smaller, more frequent meals rather than large portions Avoid high-fat, greasy, or heavily spiced foods, which can worsen nausea Eat slowly and chew food thoroughly Stay well hydrated, particularly if experiencing diarrhoea or vomiting

Although between-group differences were not statistically significant, the 10 mg group exhibited clinically meaningful improvements in HbA1c and a greater trend toward weight loss

We propose that liver-targeted TR agonists that are capable of uncoupling beneficial effects from deleterious effects could be tested in future clinical studies for the treatment of type 2 diabetes

However, visit your doctor if diarrhea occurs in infants or young children for more than several days in a row, the elderly, anyone who is underweight and already suffering from health problems, or someone who develops more serious symptoms, including: Blood or mucus in your stool Weight loss Fever Pay attention to signs that youre becoming dehydrated, and take steps to drink more water and obtain electrolytes

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