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doi: 10.1177/1060028019899152

Lauzier, A., Charbonneau, M., Paquette, M., Harper, K

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This upregulation will in turn up-regulate at the transcriptional level the expression of proinflammatory cytokines (IL-1, IL-6, IL-18, etc.), chemokines, adhesion molecules, Fas ligands33 which will activate the caspase cascades (apoptosis) and the ATP depletion from mitochondria (necrosis) leading to an autosustaining and autopotentiating oxidative loop

Membrino V, Di Paolo A, Alia S, Papiri G, Vignini A